If you have any reason to suspect your pet has ingested something toxic, please contact your veterinarian or one of the other resources listed:
• ASPCA Animal Poison Control Center 24-hour hotline at (888) 426-4435
• Pet Poison Helpline® 24-hour animal poison control service at (855) 764-7661
Enalapril
Generic Name: Enalapril
Common Names: Vasotec, Epaned
Enalapril, an ACE (angiotensin-converting enzyme) inhibitor, is often used to lower blood pressure in both human and veterinary medicine. This medication may also be used in veterinary practice as part of a heart failure therapeutic regimen. However, consumption can be toxic in pets if accidental ingestion (and thus the likelihood of overdose) occurs.
It is important to note that other ACE inhibitors (such as benazepril, lisinopril, captopril, ramipril and imidapril) carry similar toxicity risks.
Signs and symptoms of toxicity: Low blood pressure is the most common sign of toxicity. Other signs of toxicity include lack of energy, increased saliva production, increased heart rate, vomiting, diarrhea, weakness, cough, bronchospasms, and kidney dysfunction. The onset and duration of symptoms depends upon the particular ACE inhibitor ingested.
Toxic consumption: In dogs, 100 mg/kg may be toxic and 200 mg/kg may cause death.
| X-Small Yorkie, Chihuahua |
Small Pug, Boston Terrier, Poodle |
Medium Beagle, Scottish Terrier |
Large Boxer, Cocker Spaniel |
X-Large Retriever, German Shepherd |
XX-Large Great Dane, St. Bernard |
| 1 – 10 lbs. (0.45 – 4.6 kg) |
11 – 25 lbs. (5 – 11.4 kg) |
26 – 40 lbs. (11.8 – 18.2 kg) |
41 – 70 lbs. (18.6 – 31.8 kg) |
71 – 90 lbs. (32.3 – 40.9 kg) |
91 – 110 lbs. (41.4 – 50 kg) |
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| > 44 mg | > 499 mg | > 1179 mg | > 1859 mg | > 3230 mg | > 4140 mg |
References:
– Osweiler, G, et al. (2011). Blackwell’s five-minute veterinary consult clinical companion. Small Animal Toxicology. [Kindle version]. Retrieved from Amazon.com
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