Project Description
If you have any reason to suspect your pet has ingested something toxic, please contact your veterinarian or one of the other resources listed:
• ASPCA Animal Poison Control Center 24-hour hotline at (888) 426-4435
• Pet Poison Helpline® 24-hour animal poison control service at (855) 764-7661
5-Hydroxytryptophan
5-HTP, or Griffonia seed extract, is a human dietary supplement used for a variety of ailments in humans. This supplement is potentially toxic in pets as it has the ability to induce serotonin syndrome.
Signs and symptoms of toxicity: sedation, agitation, tremors, seizures, hyperthermia, GI upset, difficulty walking, abdominal pain, increased sensitivity to stimuli, and temporary blindness.
Toxic consumption: For dogs, the minimum oral toxic dose is 24 mg/kg (11 mg/lb). Oral ingestion of 128 mg/kg (58 mg/lb) by a dog may be fatal.
| X-Small Yorkie, Chihuahua |
Small Pug, Boston Terrier, Poodle |
Medium Beagle, Scottish Terrier |
Large Boxer, Cocker Spaniel |
X-Large Retriever, German Shepherd |
XX-Large Great Dane, St. Bernard |
| 1 – 10 lbs. (0.45 – 4.6 kg) |
11 – 25 lbs. (5 – 11.4 kg) |
26 – 40 lbs. (11.8 – 18.2 kg) |
41 – 70 lbs. (18.6 – 31.8 kg) |
71 – 90 lbs. (32.3 – 40.9 kg) |
91 – 110 lbs. (41.4 – 50 kg) |
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| > 10.8 mg | > 120 mg | > 283 mg | > 446 mg | > 775 mg | > 993 mg |
References:
– Peterson, M.E. & P.A. Talcott (2013). Small Animal Toxicology, 3rd Ed., Saunders. St. Louis.
Pet Poison Control is provided free as a public service by the American College of Veterinary Pharmacists. Today we’re asking you to support us with a small donation. If you would like to dedicate your gift in honor or memory of a pet or individual, you will have that option before checkout. Your gift of any amount helps us maintain this resource and make it available to the pharmacy and veterinary communities. Thank you!
