If you have any reason to suspect your pet has ingested something toxic, please contact your veterinarian or one of the other resources listed:
• ASPCA Animal Poison Control Center 24-hour hotline at (888) 426-4435
• Pet Poison Helpline® 24-hour animal poison control service at (855) 764-7661
5-Hydroxytryptophan
5-HTP, or Griffonia seed extract, is a human dietary supplement used for a variety of ailments in humans. This supplement is potentially toxic in pets as it has the ability to induce serotonin syndrome.
Signs and symptoms of toxicity: sedation, agitation, tremors, seizures, hyperthermia, GI upset, difficulty walking, abdominal pain, increased sensitivity to stimuli, and temporary blindness.
Toxic consumption: For dogs, the minimum oral toxic dose is 24 mg/kg (11 mg/lb). Oral ingestion of 128 mg/kg (58 mg/lb) by a dog may be fatal.
| X-Small Yorkie, Chihuahua |
Small Pug, Boston Terrier, Poodle |
Medium Beagle, Scottish Terrier |
Large Boxer, Cocker Spaniel |
X-Large Retriever, German Shepherd |
XX-Large Great Dane, St. Bernard |
| 1 – 10 lbs. (0.45 – 4.6 kg) |
11 – 25 lbs. (5 – 11.4 kg) |
26 – 40 lbs. (11.8 – 18.2 kg) |
41 – 70 lbs. (18.6 – 31.8 kg) |
71 – 90 lbs. (32.3 – 40.9 kg) |
91 – 110 lbs. (41.4 – 50 kg) |
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| > 10.8 mg | > 120 mg | > 283 mg | > 446 mg | > 775 mg | > 993 mg |
References:
– Peterson, M.E. & P.A. Talcott (2013). Small Animal Toxicology, 3rd Ed., Saunders. St. Louis.
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