Project Description

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If you have any reason to suspect your pet has ingested something toxic, please contact your veterinarian or the ASPCA Animal Poison Control Center 24-hour hotline at (888) 426-4435.

Amlodipine

Generic Name: amlodipine
Brand Name: Norvasc

Amlodipine, a calcium channel blocker, is commonly used in human and veterinary medicine to treat many disease states including various cardiac diseases and renal complications. Despite its use in animals, accidental overdose of amlodipine can be dangerous for pets.

Please note that other calcium channel blockers (such as diltiazem, verapamil, nefedipine, and felodipine) carry similar toxicity risks.

Signs and symptoms of toxicity: Signs of toxicity include vomiting, decreased heart rate, low blood pressure, altered mental status, diarrhea and weakness.

Toxic consumption:
There is no established toxic threshold for pet consumption. All incidents of accidental exposure should be reported immediately.

References:
- Costello M, Syring RS. Calcium channel blocker toxicity. J Vet Emerg Crit Care 2008; 18:54-60.
- Osweiler, G, et al. (2011). Blackwell’s five-minute veterinary consult clinical companion. Small Animal Toxicology. [Kindle version]. Retrieved from Amazon.com